Advances in neurostimulation for Parkisons

New England Journal of Medicine  (Excerpt) http://www.nejm.org/doi/full/10.1056/NEJMoa1205158#t=article Parkinson’s disease is a progressive neurodegenerative disease that affects dopaminergic neurotransmission, resulting in bradykinesia, rigidity, and rest tremor. After an initial honeymoon period, during which there is a sustained response to dopaminergic treatment, beneficial effects are hampered by levodopa-induced motor complications,1 progressively compromising quality of life.2-4 … more[…]